NVIDIAUnknown Architecture

Rent AMD Instinct MI250X Cloud Instances

The AMD Instinct MI250X is a high-performance data center GPU designed for demanding HPC and AI workloads. Built on the AMD CDNA 2 architecture, it offers exceptional compute capabilities and memory bandwidth, making it suitable for large-scale simulations, deep learning training, and other computat...

📊 Pricing at a Glance

Cheapest Provider
Cirrascale
$1.28/GPU/hr
Most Expensive
Cirrascale
$1.60/GPU/hr
Median Price
$1.48/GPU/hr
Total Instances
4
Providers
1
Last Updated
June 5, 2026

AMD Instinct MI250X rental pricing ranges from $1.28/GPU/hr to $1.60/GPU/hr across 4 instances from 1 providers (updated June 2026).

Looking for a specific provider? See Cirrascale AMD Instinct MI250X.

Available Offers

Compare the top 5 cheapest offers from 1 providers.

4 instances available
AMD Instinct MI250X4x
128GB VRAM
256 vCPU
1024GB RAM
11882GB Storage
$1.28/GPU/hr
$5.12/hr total (4×)
AMD Instinct MI250X4x
128GB VRAM
256 vCPU
1024GB RAM
11882GB Storage
$1.44/GPU/hr
$5.76/hr total (4×)
AMD Instinct MI250X4x
128GB VRAM
256 vCPU
1024GB RAM
11882GB Storage
$1.52/GPU/hr
$6.08/hr total (4×)
AMD Instinct MI250X4x
128GB VRAM
256 vCPU
1024GB RAM
11882GB Storage
$1.60/GPU/hr
$6.40/hr total (4×)

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Technical Specifications

CUDA cores
N/A (AMD Architecture)
Memory type
HBM2e
Tensor cores
N/A (AMD Architecture, but includes Matrix Cores)
FP8 performance
N/A
Memory bandwidth
1.6 TB/s

Strengths & Limitations

Advantages
  • Exceptional double-precision (FP64) performance, crucial for scientific computing.
  • High memory bandwidth with HBM2e, enabling faster data transfer.
  • Optimized for large-scale HPC and AI workloads.
  • Strong performance in specific AI training tasks.
  • Advanced features for virtualization and security.
Limitations
  • Higher hourly cost compared to many NVIDIA GPUs (e.g., significantly more expensive than an NVIDIA H100 PCIe at $1.07/hr).
  • Software ecosystem and tooling may not be as mature as NVIDIA's CUDA ecosystem.
  • Performance in certain AI tasks may lag behind NVIDIA's offerings.
  • Limited availability compared to some NVIDIA GPUs.
  • Power consumption can be high.

Top Use Cases

High-Performance Computing (HPC)

Ideal for running complex simulations in fields like weather forecasting, computational fluid dynamics, and materials science, leveraging its strong FP64 performance and memory bandwidth.

Large-Scale AI Training

Suitable for training large deep learning models, particularly those requiring high memory capacity and bandwidth, such as natural language processing models.

Scientific Research

Enables researchers to accelerate their work in various scientific domains by providing the necessary compute power for data analysis, modeling, and simulation.

Real-World Benchmark

HPC and AI Performance
The AMD Instinct MI250X delivers competitive performance in HPC benchmarks and specific AI training workloads. However, its performance relative to NVIDIA GPUs can vary depending on the specific application and optimization level. Independent benchmarks are essential for evaluating its suitability for specific use cases.
Est. Cost$5.12/hr

Market Analysis

The AMD Instinct MI250X competes with NVIDIA's high-end data center GPUs, such as the A100 and H100. It offers a compelling alternative for users who prioritize FP64 performance and are comfortable with the AMD software ecosystem. However, its higher cost compared to some NVIDIA options may be a barrier for some users. The market is rapidly evolving, with new GPUs from both AMD and NVIDIA constantly being released, so staying up-to-date with the latest benchmarks is crucial.

Frequently Asked Questions

What is the AMD CDNA 2 architecture?â–¾

AMD CDNA 2 is AMD's second-generation data center GPU architecture, designed for high-performance computing and AI workloads. It features enhanced compute units, improved memory bandwidth, and advanced features for virtualization and security.

Is the MI250X suitable for gaming?â–¾

No, the AMD Instinct MI250X is designed for data center workloads and is not optimized for gaming. Consumer-grade GPUs like the GeForce RTX series are better suited for gaming applications.

What software tools are available for developing applications on the MI250X?â–¾

AMD provides the ROCm (Radeon Open Compute) platform, which includes compilers, libraries, and tools for developing and deploying applications on AMD GPUs. While ROCm is powerful, the CUDA ecosystem from NVIDIA is often considered more mature and widely adopted.

Alternative GPUs

NVIDIA H100 PCIe
$1.07/hr

Offers potentially better performance in many AI training tasks and has a more mature software ecosystem, but may not match the MI250X's FP64 performance. Significantly cheaper.

NVIDIA A100 PCIe 80GB
$0.12/hr

A previous-generation high-performance GPU that may offer a better price-performance ratio for some workloads, especially if FP64 performance is not critical. Much cheaper.

AMD Instinct MI300X
$0.50/hr

A newer generation AMD GPU that may offer improved performance and features, depending on availability and specific workload requirements. Significantly cheaper.

Cite This Data
This pricing data is updated daily and free to cite with attribution.
Source: GPUPerHour.com — AMD Instinct MI250X GPU Rental Pricing Comparison (June 2026)

Journalists, bloggers, and researchers: You're welcome to cite our data in your articles with attribution. Our pricing database is updated in real-time from 1+ cloud providers.

MI250X Pricing: What It Costs in 2026

â–¾

MI250X cloud GPU pricing ranges from $1.28/hr on Cirrascale to $1.60/hr on Cirrascale, based on 4 offers tracked by GPUPerHour across 1 provider. 4 instances are currently in stock across 1 region.

Running a MI250X continuously for one month at the cheapest available rate costs approximately $922. Most providers bill per second or per minute, so shorter jobs cost proportionally less. Prices on GPUPerHour update every 60 seconds, reflecting real-time changes in provider pricing and availability.

How MI250X Compares

â–¾

Compared to alternatives, the NVIDIA H100 PCIe is available from $1.07/hr. Offers potentially better performance in many AI training tasks and has a more mature software ecosystem, but may not match the MI250X's FP64 performance. Significantly cheaper. The NVIDIA A100 PCIe 80GB is available from $0.12/hr. A previous-generation high-performance GPU that may offer a better price-performance ratio for some workloads, especially if FP64 performance is not critical. Much cheaper. The AMD Instinct MI300X is available from $0.50/hr. A newer generation AMD GPU that may offer improved performance and features, depending on availability and specific workload requirements. Significantly cheaper.

For detailed head-to-head analysis, see: a10 vs mi250x, a100 pcie 40gb vs mi250x, a100 pcie 80gb vs mi250x.

MI250X Pricing FAQ

How much does MI250X cost per hour?â–¾

MI250X cloud rental pricing starts at $1.28/hr on Cirrascale and goes up to $1.60/hr. Running a MI250X continuously for one month at the cheapest rate costs approximately $922. GPUPerHour tracks pricing from 1 provider with prices updated every 60 seconds.

What are the alternatives to MI250X?â–¾

Alternatives to the MI250X include NVIDIA H100 PCIe ($1.07/hr), NVIDIA A100 PCIe 80GB ($0.12/hr), AMD Instinct MI300X ($0.50/hr). Offers potentially better performance in many AI training tasks and has a more mature software ecosystem, but may not match the MI250X's FP64 performance. Significantly cheaper.

MI250X Price: $5.12/hr on Cirrascale | GPUPerHour