MI355X vs RTX A4500

CDNA 4vsAmpereUpdated 35 days ago

The MI355X is the clear winner for demanding AI and HPC use cases like LLM training, delivering 2300 TFLOPS FP16 and 288 GB VRAM against the A4500's 19.2 TFLOPS and 16 GB. Despite lacking live pricing, its specs dominate high-throughput scenarios where performance trumps the A4500's availability at $0.10 per hour.

RTX A4500 from $0.08/hr

Specifications Compared

SpecMI355XRTX-A4000
TDP750W140W
VRAM288 GB16 GB
Memory TypeHBM3eGDDR6
ArchitectureCDNA 4Ampere
Form FactorsOAMPCIe
InterconnectInfinity Fabric
FP8 Performance4,600 TFLOPS
FP16 Performance2,300 TFLOPS19.2 TFLOPS
FP32 Performance2300 TFLOPS19.2 TFLOPS
FP64 Performance72 TFLOPS
INT8 Performance4,600 TOPS
Memory Bandwidth8,000 GB/s448 GB/s

Performance Analysis

The MI355X vastly outpaces the A4500 in compute throughput: 2300 TFLOPS FP16 and FP32 enable training massive models at scales impossible on the A4500's 19.2 TFLOPS, reducing epochs from days to hours for datasets exceeding 16 GB VRAM. Equal FP16 and FP32 ratios on the MI355X optimize mixed-precision training, while the A4500 struggles with memory-bound tasks due to its lower figures.

Memory bandwidth defines real-world bottlenecks: the MI355X's 8000 GB/s supports enormous batch sizes in LLM training or inference, handling models with billions of parameters without swapping, unlike the A4500's 448 GB/s which limits batches to small sizes and increases latency. For inference, the MI355X's FP8 at 4600 TFLOPS accelerates high-throughput serving, making it ideal for production AI where the A4500 suffices only for prototyping.

Power efficiency tilts toward the A4500 at 140W versus 750W, but the MI355X's raw specs deliver over 100x FP16 uplift, prioritizing performance density in dense racks.

Live Cloud Pricing

Real-time prices from 25+ providers. Updated every 60 seconds.

RTX A4500

ProviderGPU ModelVRAMHost SpecsRegionPriceStatusAction
TensorDock
TensorDock
NVIDIA RTX A4000
16GB VRAM
$0.08/GPU/hr
Available
Vast.ai
Vast.ai
8×NVIDIA RTX A4000
16GB VRAM
$0.15/GPU/hr
$1.17/hr total (8×)
Available
Hyperstack
Hyperstack
4×NVIDIA RTX A4000
16GB VRAM
$0.15/GPU/hr
$0.60/hr total (4×)
Available
Hyperstack
Hyperstack
2×NVIDIA RTX A4000
16GB VRAM
$0.15/GPU/hr
$0.30/hr total (2×)
Available
Hyperstack
Hyperstack
NVIDIA RTX A4000
16GB VRAM
$0.15/GPU/hr
Available

Compare real-time pricing across 25+ providers

When to Choose the MI355X

The MI355X excels in large-scale AI training and HPC simulations requiring 288 GB HBM3e VRAM, such as training LLMs with over 100 billion parameters or scientific computing with terabyte datasets. Its 8000 GB/s bandwidth and 2300 TFLOPS FP32 ensure handling massive batch sizes without bottlenecks, ideal for research labs or enterprises building frontier models.

When to Choose the RTX A4500

The A4500 suits budget-conscious users with lighter workloads like visualization, small-scale inference, or development, available from $0.10 per hour. Its 140W TDP and PCIe form factor enable easy deployment in single-GPU cloud instances or laptops, where 16 GB GDDR6 and 19.2 TFLOPS FP16 meet needs without overprovisioning.

Use Cases

LLM Training
MI355X

The MI355X's 288 GB HBM3e VRAM and 2300 TFLOPS FP16 handle massive models and datasets, far beyond the A4500's 16 GB and 19.2 TFLOPS.

LLM Inference
MI355X

With 8000 GB/s bandwidth and FP8 at 4600 TFLOPS, the MI355X supports high-batch inference; the A4500's 448 GB/s limits scale.

Fine-tuning
MI355X

MI355X 2300 TFLOPS FP32 accelerates fine-tuning large models; A4500's 19.2 TFLOPS suits only small adapters.

Stable Diffusion
RTX A4500

A4500's 16 GB GDDR6 and $0.10 per hour pricing fit image generation prototyping; MI355X overkill for typical resolutions.

Scientific Computing
MI355X

MI355X Infinity Fabric and 288 GB VRAM enable large simulations; A4500's PCIe lacks cluster scalability.

Frequently Asked Questions

Which GPU has more VRAM?

The MI355X offers 288 GB HBM3e VRAM. The A4500 provides 16 GB GDDR6. This gap suits datacenter-scale models on MI355X.

What is the memory bandwidth difference?

MI355X delivers 8000 GB/s. A4500 achieves 448 GB/s. Higher bandwidth on MI355X boosts large batch processing.

How do FP16 performances compare?

MI355X reaches 2300 TFLOPS FP16. A4500 hits 19.2 TFLOPS FP16. MI355X excels in AI acceleration.

What are the TDPs?

MI355X consumes 750W. A4500 uses 140W. Lower TDP makes A4500 efficient for edge use.

Is there cloud pricing available?

MI355X has no live offers. A4500 starts at $0.10 per hour, averaging $0.19 per hour across four providers.

What architectures do they use?

MI355X uses CDNA 4 from 2025. A4500 employs Ampere from 2021. Newer CDNA 4 optimizes HPC.

Which is cheaper to rent, the MI355X or the RTX A4000?

Cloud rental prices for both the MI355X and RTX A4000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI355X have compared to the RTX A4000?

The MI355X has 288 GB of HBM3e memory. The RTX A4000 has 16 GB of GDDR6 memory.

Can I find MI355X and RTX A4000 GPUs available to rent right now?

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI355X and the RTX A4000?

The MI355X uses the CDNA 4 architecture (2025) while the RTX A4000 uses Ampere (2021). The MI355X delivers 119.8x the FP16 throughput and 17.9x the memory bandwidth of the RTX A4000.