MI355X vs RTX 4500 Ada

CDNA 4vsAda LovelaceUpdated 35 days ago

For dominant AI and HPC use cases like large-scale training and inference, the MI355X emerges as the clear winner: its 2300 TFLOPS FP16/FP32 and 288 GB VRAM vastly outpace the RTX 4500 Ada's 39.6 TFLOPS and 24 GB, enabling unprecedented model sizes despite higher 750W power needs.

RTX 4500 Ada from $0.74/hr

Specifications Compared

SpecMI355XRTX-4500-ADA
TDP750W210W
VRAM288 GB24 GB
Memory TypeHBM3eGDDR6
ArchitectureCDNA 4Ada Lovelace
Form FactorsOAMPCIe
InterconnectInfinity Fabric
FP8 Performance4,600 TFLOPS
FP16 Performance2,300 TFLOPS39.6 TFLOPS
FP32 Performance2300 TFLOPS39.6 TFLOPS
FP64 Performance72 TFLOPS
INT8 Performance4,600 TOPS634 TOPS
Memory Bandwidth8,000 GB/s432 GB/s

Performance Analysis

Compute capabilities define the core disparity: the MI355X delivers 2300 TFLOPS in both FP16 and FP32, exceeding the RTX 4500 Ada's 39.6 TFLOPS by a factor of 58 in these precisions. This gap accelerates AI training epochs and inference throughput on the MI355X, enabling handling of models infeasible on the RTX 4500 Ada. The MI355X's FP8 performance at 4600 TFLOPS further optimizes low-precision inference, a feature not specified for the competitor.

Memory specifications profoundly impact workloads: 288 GB HBM3e on the MI355X supports enormous batch sizes and multi-GPU model parallelism, unconstrained by the RTX 4500 Ada's 24 GB GDDR6 limit. The 8000 GB/s bandwidth versus 432 GB/s minimizes data transfer bottlenecks during training, allowing sustained high utilization. In practice, these traits position the MI355X for large language model training, while the RTX 4500 Ada suits smaller batches where its 210W TDP enables efficient single-node operation compared to 750W.

Live Cloud Pricing

Real-time prices from 25+ providers. Updated every 60 seconds.

RTX 4500 Ada

ProviderGPU ModelVRAMHost SpecsRegionPriceStatusAction
RunPod
RunPod
NVIDIA RTX 4500 Ada
24GB VRAM
$0.74/GPU/hr

Compare real-time pricing across 25+ providers

When to Choose the MI355X

The MI355X excels in datacenter environments demanding extreme scale, such as training massive AI models requiring over 24 GB VRAM. Its 288 GB HBM3e capacity and 8000 GB/s bandwidth handle large batch sizes without fragmentation, ideal for HPC clusters linked via Infinity Fabric. Users prioritizing raw performance at 2300 TFLOPS FP16 benefit despite the 750W TDP and OAM form factor.

When to Choose the RTX 4500 Ada

The RTX 4500 Ada suits prototyping, fine-tuning, and inference on mid-sized models fitting within 24 GB GDDR6. Its PCIe form factor and 210W TDP facilitate easy workstation integration with low power draw. Current cloud availability from $0.34 per hour makes it practical for immediate, cost-effective tasks without the MI355X's unlisted pricing.

Use Cases

LLM Training
MI355X

The MI355X's 288 GB HBM3e VRAM accommodates massive models, and 2300 TFLOPS FP16 accelerates training epochs far beyond the RTX 4500 Ada's 24 GB and 39.6 TFLOPS.

LLM Inference
MI355X

FP8 performance at 4600 TFLOPS on the MI355X optimizes high-throughput inference, supported by 8000 GB/s bandwidth for large batches unavailable on the RTX 4500 Ada.

Fine-tuning
RTX 4500 Ada

Most fine-tuning fits within 24 GB GDDR6, where the RTX 4500 Ada's $0.34 per hour pricing and 210W TDP provide cost-effective access versus the MI355X's scale.

Stable Diffusion
RTX 4500 Ada

Stable Diffusion workloads thrive on workstation GPUs like the RTX 4500 Ada with 39.6 TFLOPS FP16 and PCIe compatibility for rapid iteration.

Scientific Computing
MI355X

The MI355X's 2300 TFLOPS FP32 and Infinity Fabric interconnect excel in parallel simulations, surpassing the RTX 4500 Ada's 39.6 TFLOPS.

Frequently Asked Questions

What is the VRAM difference between MI355X and RTX 4500 Ada?

The MI355X features 288 GB of HBM3e VRAM, compared to the RTX 4500 Ada's 24 GB GDDR6. This 12-fold increase enables the MI355X to load vastly larger models without offloading.

How do FP16 performances compare?

MI355X achieves 2300 TFLOPS in FP16, while RTX 4500 Ada reaches 39.6 TFLOPS. The MI355X thus offers approximately 58 times higher throughput for AI tasks.

What are the power requirements?

The MI355X has a 750W TDP, contrasting the RTX 4500 Ada's 210W. Lower power on the NVIDIA card suits dense workstation setups.

Is the RTX 4500 Ada available in the cloud?

Yes, RTX 4500 Ada offers start from $0.34 per hour, averaging $0.51 per hour across three providers. MI355X has no live offers currently.

What architectures power these GPUs?

MI355X uses CDNA 4 from 2025 for datacenter AI, while RTX 4500 Ada employs Ada Lovelace from 2023 for professional graphics.

How does memory bandwidth differ?

MI355X provides 8000 GB/s bandwidth with HBM3e, versus RTX 4500 Ada's 432 GB/s on GDDR6. This supports larger batches on the AMD GPU.

Which is cheaper to rent, the MI355X or the RTX 4500 Ada?

Cloud rental prices for both the MI355X and RTX 4500 Ada vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI355X have compared to the RTX 4500 Ada?

The MI355X has 288 GB of HBM3e memory. The RTX 4500 Ada has 24 GB of GDDR6 memory.

Can I find MI355X and RTX 4500 Ada GPUs available to rent right now?

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI355X and the RTX 4500 Ada?

The MI355X uses the CDNA 4 architecture (2025) while the RTX 4500 Ada uses Ada Lovelace (2023). The MI355X delivers 58.1x the FP16 throughput and 18.5x the memory bandwidth of the RTX 4500 Ada.