MI300X vs RTX 3080

CDNA 3vsAmpereUpdated 36 days ago

The MI300X emerges as the superior choice for prevalent AI and HPC workloads. Its 1307 TFLOPS FP16, 192 GB VRAM, and 5300 GB/s bandwidth enable scaling massive models infeasible on the RTX 3080's 29.8 TFLOPS and 10 to 12 GB limits, justifying the higher $2.63 average hourly cost for production throughput.

MI300X from $1.99/hr

Specifications Compared

SpecMI300XRTX-3080
TDP750W320W
VRAM192 GB10-12 GB
Memory TypeHBM3GDDR6X
ArchitectureCDNA 3Ampere
Form FactorsOAMPCIe
InterconnectInfinity Fabric, PCIe 5.0
FP8 Performance2,614 TFLOPS
FP16 Performance1,307 TFLOPS29.8 TFLOPS
FP32 Performance163 TFLOPS29.8 TFLOPS
FP64 Performance81.7 TFLOPS
INT8 Performance2,614 TOPS
Memory Bandwidth5,300 GB/s760 GB/s

Performance Analysis

The MI300X's FP16 performance reaches 1307 TFLOPS, over 43 times the RTX 3080's 29.8 TFLOPS, accelerating deep learning training where half-precision dominates. This delta translates to faster convergence on large datasets, reducing epochs from days to hours on the MI300X. FP32 at 163 TFLOPS on the MI300X still surpasses the RTX 3080's 29.8 TFLOPS, benefiting simulations requiring full precision.

Memory capacity defines workload feasibility: 192 GB HBM3 on the MI300X supports massive batch sizes for models exceeding 70 billion parameters, while 10 to 12 GB GDDR6X on the RTX 3080 restricts users to small batches or model sharding. Bandwidth at 5300 GB/s versus 760 GB/s minimizes bottlenecks in data-intensive inference, enabling higher throughput without stalling. The MI300X's FP8 at 2614 TFLOPS further optimizes low-precision inference, cutting latency by orders of magnitude over the RTX 3080.

Power draw reflects efficiency trade-offs: the MI300X's 750W TDP suits dense clusters, while the RTX 3080's 320W fits edge or desktop use, though at reduced scale.

Live Cloud Pricing

Real-time prices from 25+ providers. Updated every 60 seconds.

MI300X

ProviderGPU ModelVRAMHost SpecsRegionPriceStatusAction
RunPod
RunPod
AMD Instinct MI300X
192GB VRAM
$1.99/GPU/hr
Hot Aisle
Hot Aisle
AMD Instinct MI300X
192GB VRAM
$1.99/GPU/hr
Available
Cirrascale
Cirrascale
8×AMD Instinct MI300X
192GB VRAM
$3.08/GPU/hr
$24.64/hr total (8×)
Crusoe
Crusoe
AMD Instinct MI300X
192GB VRAM
$3.45/GPU/hr
Cirrascale
Cirrascale
8×AMD Instinct MI300X
192GB VRAM
$3.47/GPU/hr
$27.76/hr total (8×)

Compare real-time pricing across 25+ providers

When to Choose the MI300X

Opt for the MI300X in large-scale AI training or inference where VRAM exceeds 12 GB, such as processing 175 billion parameter models: its 192 GB HBM3 handles full context without offloading. High-bandwidth tasks benefit from 5300 GB/s, supporting batch sizes up to 512 versus the RTX 3080's limits around 8 to 16. Datacenter deployments leverage Infinity Fabric and PCIe 5.0 for multi-GPU scaling at 1307 TFLOPS FP16.

When to Choose the RTX 3080

Select the RTX 3080 for budget-conscious prototyping or gaming-integrated workflows: its $0.06 per hour starting price enables experimentation at 1/8th the MI300X's $0.50 minimum. Small models under 7 billion parameters fit within 10 to 12 GB GDDR6X, with 29.8 TFLOPS FP16 sufficing for fine-tuning or Stable Diffusion at low cost. Lower 320W TDP reduces cooling needs in personal or small cloud instances.

Use Cases

LLM Training
MI300X

The MI300X's 192 GB HBM3 VRAM and 1307 TFLOPS FP16 support training models over 100 billion parameters without sharding. RTX 3080's 10 to 12 GB restricts it to tiny datasets.

LLM Inference
MI300X

2614 TFLOPS FP8 on the MI300X delivers ultra-low latency for high-concurrency serving. RTX 3080's 29.8 TFLOPS FP16 limits throughput to low-volume queries.

Fine-tuning
MI300X

MI300X handles full model fine-tuning with 163 TFLOPS FP32 and 5300 GB/s bandwidth for large batches. RTX 3080 suits only LoRA on small models due to VRAM constraints.

Stable Diffusion
RTX 3080

RTX 3080 generates images efficiently at 29.8 TFLOPS with 10 to 12 GB VRAM for 512x512 resolutions. MI300X's scale and $2.63 hourly average exceed needs for creative tasks.

Scientific Computing
MI300X

MI300X excels in simulations via 192 GB VRAM and PCIe 5.0 interconnect for multi-node jobs. RTX 3080's 760 GB/s bandwidth bottlenecks complex datasets.

Frequently Asked Questions

How much more VRAM does the MI300X have than the RTX 3080?

The MI300X offers 192 GB HBM3, which is 16 to 19 times the RTX 3080's 10 to 12 GB GDDR6X. This enables loading massive models without CPU offload. Batch sizes scale dramatically as a result.

What is the FP16 performance difference between MI300X and RTX 3080?

MI300X achieves 1307 TFLOPS FP16, approximately 44 times the RTX 3080's 29.8 TFLOPS. Training times drop proportionally for deep learning. Inference benefits similarly in mixed precision.

Which GPU is cheaper in the cloud?

RTX 3080 starts at $0.06 per hour averaging $0.15 across ten offers, versus MI300X at $0.50 minimum and $2.63 average over nine. Budget tasks favor RTX 3080. High-performance needs justify MI300X costs.

Does MI300X support FP8 compute?

MI300X delivers 2614 TFLOPS FP8 for optimized inference. RTX 3080 lacks native FP8, relying on FP16 at 29.8 TFLOPS. This gap accelerates quantized LLM serving on MI300X.

What are the power requirements?

MI300X draws 750W TDP for datacenter density, while RTX 3080 uses 320W for consumer setups. Efficiency per watt favors MI300X in FP16 at 1.74 TFLOPS/W versus 0.09 TFLOPS/W. Cooling scales with deployment.

Can RTX 3080 handle large language models?

RTX 3080's 10 to 12 GB VRAM limits it to models under 7 billion parameters. MI300X's 192 GB supports 70B+ models fully. Use RTX 3080 for testing, MI300X for production.

Which is cheaper to rent, the MI300X or the RTX 3080?

Cloud rental prices for both the MI300X and RTX 3080 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI300X have compared to the RTX 3080?

The MI300X has 192 GB of HBM3 memory. The RTX 3080 has 10 to 12 GB of GDDR6X memory.

Can I find MI300X and RTX 3080 GPUs available to rent right now?

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI300X and the RTX 3080?

The MI300X uses the CDNA 3 architecture (2023) while the RTX 3080 uses Ampere (2020). The MI300X delivers 43.9x the FP16 throughput and 7.0x the memory bandwidth of the RTX 3080.

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