MI300X vs Quadro RTX 8000

CDNA 3vsTuringUpdated 36 days ago

The MI300X emerges as the clear winner for prevalent AI and HPC use cases: 1307 TFLOPS FP16 and 192 GB VRAM outperform RTX 8000's 16.3 TFLOPS and 48 GB by orders of magnitude, enabling modern workloads. Cloud pricing from $0.50 per hour further tilts value toward MI300X despite higher TDP.

MI300X from $1.99/hr

Specifications Compared

SpecMI300XQUADRO-RTX-8000
TDP750W260W
VRAM192 GB48 GB
Memory TypeHBM3GDDR6
ArchitectureCDNA 3Turing
Form FactorsOAMPCIe
InterconnectInfinity Fabric, PCIe 5.0NVLink
FP8 Performance2,614 TFLOPS
FP16 Performance1,307 TFLOPS16.3 TFLOPS
FP32 Performance163 TFLOPS16.3 TFLOPS
FP64 Performance81.7 TFLOPS
INT8 Performance2,614 TOPS
Memory Bandwidth5,300 GB/s672 GB/s

Performance Analysis

Memory capacity defines a core disparity: the MI300X's 192 GB HBM3 supports batch sizes for models exceeding hundreds of billions of parameters, while the RTX 8000's 48 GB GDDR6 limits it to smaller datasets. Bandwidth amplifies this: 5300 GB/s on MI300X enables rapid data movement for training loops, reducing bottlenecks in inference at scale, compared to 672 GB/s on RTX 8000 which suits moderate workloads.

Compute throughput reveals AI specialization: MI300X FP16 at 1307 TFLOPS accelerates mixed-precision training, where FP32 at 163 TFLOPS handles simulations; RTX 8000 matches 16.3 TFLOPS in both, adequate for legacy FP32-dominant tasks but insufficient for modern deep learning. FP8 on MI300X reaches 2614 TFLOPS, optimizing low-precision inference absent on RTX 8000.

Power draw impacts deployment: MI300X's 750W TDP demands robust cooling for datacenters, versus RTX 8000's efficient 260W for workstations, influencing total cost of ownership in edge computing.

Live Cloud Pricing

Real-time prices from 25+ providers. Updated every 60 seconds.

MI300X

ProviderGPU ModelVRAMHost SpecsRegionPriceStatusAction
RunPod
RunPod
AMD Instinct MI300X
192GB VRAM
$1.99/GPU/hr
Hot Aisle
Hot Aisle
AMD Instinct MI300X
192GB VRAM
$1.99/GPU/hr
Available
Cirrascale
Cirrascale
8×AMD Instinct MI300X
192GB VRAM
$3.08/GPU/hr
$24.64/hr total (8×)
Crusoe
Crusoe
AMD Instinct MI300X
192GB VRAM
$3.45/GPU/hr
Cirrascale
Cirrascale
8×AMD Instinct MI300X
192GB VRAM
$3.47/GPU/hr
$27.76/hr total (8×)

Compare real-time pricing across 25+ providers

When to Choose the MI300X

The MI300X excels in datacenter-scale AI training and inference: its 192 GB VRAM and 5300 GB/s bandwidth handle large language models with batch sizes infeasible on 48 GB alternatives. Cloud availability from $0.50 per hour suits bursty workloads without upfront hardware costs.

Scientific simulations benefit from 1307 TFLOPS FP16 and Infinity Fabric interconnects, enabling distributed computing across PCIe 5.0 nodes.

When to Choose the Quadro RTX 8000

The RTX 8000 fits legacy workstation upgrades: its PCIe form factor and 260W TDP integrate easily into existing professional setups for CAD or rendering. NVLink supports multi-GPU visualization where 16.3 TFLOPS FP32 suffices for real-time tasks.

Power-sensitive environments or used hardware budgets favor it, as no cloud offers exist, avoiding MI300X's 750W demands.

Use Cases

LLM Training
MI300X

MI300X's 1307 TFLOPS FP16 and 192 GB VRAM support massive batch sizes for training billion-parameter models. RTX 8000's 16.3 TFLOPS and 48 GB limit it to small-scale experiments.

LLM Inference
MI300X

2614 TFLOPS FP8 and 5300 GB/s bandwidth on MI300X deliver high-throughput serving. RTX 8000 cannot compete with 672 GB/s for production-scale queries.

Fine-tuning
MI300X

163 TFLOPS FP32 and HBM3 enable efficient parameter updates on large models. RTX 8000's matching 16.3 TFLOPS FP32 restricts dataset sizes.

Stable Diffusion
Either

MI300X accelerates generation with 1307 TFLOPS FP16 for high-res outputs. RTX 8000 handles standard resolutions at 16.3 TFLOPS in workstations.

Scientific Computing
MI300X

Infinity Fabric and 5300 GB/s bandwidth optimize simulations. RTX 8000's NVLink suits smaller clusters but lacks capacity.

Frequently Asked Questions

What is the VRAM difference between MI300X and Quadro RTX 8000?

MI300X provides 192 GB HBM3, enabling large model handling. Quadro RTX 8000 offers 48 GB GDDR6, suitable for moderate datasets. This quadruples capacity for MI300X.

How do FP16 performance levels compare?

MI300X achieves 1307 TFLOPS in FP16 for AI acceleration. Quadro RTX 8000 reaches 16.3 TFLOPS, about 80 times lower. MI300X dominates training tasks.

What are the cloud pricing options?

MI300X rentals start at $0.50 per hour, averaging $2.63 across nine providers. Quadro RTX 8000 has no live cloud offers. On-premises purchase applies for RTX 8000.

Which has higher memory bandwidth?

MI300X delivers 5300 GB/s with HBM3. Quadro RTX 8000 provides 672 GB/s via GDDR6. Nearly eightfold advantage aids MI300X in data-intensive jobs.

Compare power consumption and form factors?

MI300X uses 750W in OAM for datacenters. Quadro RTX 8000 draws 260W in PCIe for workstations. RTX 8000 suits lower-power setups.

Is MI300X better for LLM workloads?

Yes, with 2614 TFLOPS FP8 and 192 GB VRAM for inference. RTX 8000's 16.3 TFLOPS limits it to prototypes. MI300X scales production.

Which is cheaper to rent, the MI300X or the Quadro RTX 8000?

Cloud rental prices for both the MI300X and Quadro RTX 8000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI300X have compared to the Quadro RTX 8000?

The MI300X has 192 GB of HBM3 memory. The Quadro RTX 8000 has 48 GB of GDDR6 memory.

Can I find MI300X and Quadro RTX 8000 GPUs available to rent right now?

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI300X and the Quadro RTX 8000?

The MI300X uses the CDNA 3 architecture (2023) while the Quadro RTX 8000 uses Turing (2018). The MI300X delivers 80.2x the FP16 throughput and 7.9x the memory bandwidth of the Quadro RTX 8000.

MI300X vs Quadro RTX 8000: AMD 192GB vs NVIDIA 48GB | GPUPerHour