Specifications Compared
| Spec | MI300X | QUADRO-RTX-4000 |
|---|---|---|
| TDP | 750W | 160W |
| VRAM | 192 GB | 8 GB |
| Memory Type | HBM3 | GDDR6 |
| Architecture | CDNA 3 | Turing |
| Form Factors | OAM | PCIe |
| Interconnect | Infinity Fabric, PCIe 5.0 | |
| FP8 Performance | 2,614 TFLOPS | |
| FP16 Performance | 1,307 TFLOPS | 7.1 TFLOPS |
| FP32 Performance | 163 TFLOPS | 7.1 TFLOPS |
| FP64 Performance | 81.7 TFLOPS | |
| INT8 Performance | 2,614 TOPS | |
| Memory Bandwidth | 5,300 GB/s | 416 GB/s |
Performance Analysis
MI300X dominates in AI workloads due to its 1307 TFLOPS FP16 performance, over 184 times higher than Quadro RTX 4000's 7.1 TFLOPS: this accelerates training and inference where half-precision dominates. MI300X's FP32 at 163 TFLOPS, more than 22 times Quadro's 7.1 TFLOPS, aids general-purpose computing like simulations. The FP16/FP32 ratio on MI300X favors AI tensor operations, while Quadro's parity suits graphics but limits ML scale.
Memory specs transform real-world usage: 192 GB HBM3 on MI300X enables massive batch sizes for training large models without swapping, supported by 5300 GB/s bandwidth that feeds compute units efficiently. Quadro's 8 GB GDDR6 and 416 GB/s restrict it to small batches or models under 8 GB, causing frequent data stalls in deep learning.
Power draw underscores deployment differences, with MI300X's 750W TDP enabling dense racks for exascale compute versus Quadro's efficient 160W for edge or desktop inference.
Live Cloud Pricing
Real-time prices from 25+ providers. Updated every 60 seconds.
MI300X
| Provider | GPU Model | VRAM | Host Specs | Region | Price | Status | Action | |
|---|---|---|---|---|---|---|---|---|
![]() RunPod | AMD Instinct MI300X 192GB VRAM | 192GB | 24 vCPU 256GB RAM | 🌍global | $1.99/GPU/hr | |||
![]() Hot Aisle | AMD Instinct MI300X 192GB VRAM | 192GB | 8 vCPU 224GB RAM 12288GB Storage | Michigan | $1.99/GPU/hr | Available | ||
Cirrascale | 8×AMD Instinct MI300X 192GB VRAM | 192GB | 192 vCPU 2355GB RAM 44538GB Storage | United States | $3.08/GPU/hr $24.64/hr total (8×) | |||
![]() Crusoe | AMD Instinct MI300X 192GB VRAM | 192GB | 0 vCPU 0GB RAM | United States | $3.45/GPU/hr | |||
Cirrascale | 8×AMD Instinct MI300X 192GB VRAM | 192GB | 192 vCPU 2355GB RAM 44538GB Storage | United States | $3.47/GPU/hr $27.76/hr total (8×) |
Quadro RTX 4000
| Provider | GPU Model | VRAM | Host Specs | Region | Price | Status | Action | |
|---|---|---|---|---|---|---|---|---|
![]() Paperspace | NVIDIA Quadro RTX 4000 8GB VRAM | 8GB | 8 vCPU 30GB RAM 50GB Storage | New York | $0.56/GPU/hr | Available | ||
![]() Paperspace | NVIDIA Quadro RTX 4000 8GB VRAM | 8GB | 8 vCPU 30GB RAM 50GB Storage | Canada | $0.56/GPU/hr | Available | ||
![]() Paperspace | 2×NVIDIA Quadro RTX 4000 8GB VRAM | 8GB | 16 vCPU 60GB RAM 50GB Storage | New York | $0.56/GPU/hr $1.12/hr total (2×) | Available | ||
![]() Paperspace | NVIDIA Quadro RTX 4000 8GB VRAM | 8GB | 8 vCPU 30GB RAM 50GB Storage | Amsterdam | $0.56/GPU/hr | Available | ||
![]() Paperspace | 2×NVIDIA Quadro RTX 4000 8GB VRAM | 8GB | 16 vCPU 60GB RAM 50GB Storage | Canada | $0.56/GPU/hr $1.12/hr total (2×) | Available |
When to Choose the MI300X
Select MI300X for large-scale AI training or inference: its 192 GB VRAM accommodates models exceeding 70B parameters, and 1307 TFLOPS FP16 cuts training times dramatically. FP8 performance at 2614 TFLOPS optimizes high-throughput serving in datacenters. High bandwidth of 5300 GB/s supports enormous batch sizes, ideal for HPC simulations or fine-tuning on vast datasets.
When to Choose the Quadro RTX 4000
Choose Quadro RTX 4000 for budget-conscious professional visualization or small ML tasks: 8 GB VRAM handles CAD models or Stable Diffusion at modest resolutions, with consistent 7.1 TFLOPS FP16/FP32 for real-time rendering. Low 160W TDP and average pricing of $0.56/hr fit power-limited workstations or light cloud prototyping without overprovisioning.
Use Cases
MI300X's 192 GB VRAM and 1307 TFLOPS FP16 enable training of models over 100B parameters with large batches. Quadro RTX 4000's 8 GB VRAM cannot handle such scales.
2614 TFLOPS FP8 on MI300X supports high-throughput serving for massive LLMs. Quadro's 7.1 TFLOPS FP16 limits it to tiny models.
163 TFLOPS FP32 and 5300 GB/s bandwidth on MI300X accelerate fine-tuning on large datasets. Quadro RTX 4000 struggles with memory constraints beyond small adapters.
Quadro RTX 4000's 8 GB suffices for standard image generation at 7.1 TFLOPS FP16. MI300X excels for high-res batch processing but is overkill for singles.
MI300X's 192 GB HBM3 and Infinity Fabric scaling suit large simulations. Quadro RTX 4000's PCIe form limits multi-GPU HPC setups.
Frequently Asked Questions
What is the VRAM difference between MI300X and Quadro RTX 4000?▾
MI300X features 192 GB HBM3 VRAM, enabling massive models. Quadro RTX 4000 has 8 GB GDDR6, suitable only for smaller workloads.
How do FP16 performances compare?▾
MI300X delivers 1307 TFLOPS FP16 for rapid AI tasks. Quadro RTX 4000 provides 7.1 TFLOPS, about 184 times lower.
Which has higher memory bandwidth?▾
MI300X offers 5300 GB/s, supporting large batch training. Quadro RTX 4000 reaches 416 GB/s, limiting data throughput.
What are the cloud pricing ranges?▾
MI300X starts at $0.50/hr, averaging $2.63/hr across 9 offers. Quadro RTX 4000 is from $0.56/hr, averaging $0.56/hr over 5 offers.
Is MI300X better for AI training?▾
Yes, MI300X's 1307 TFLOPS FP16 and 192 GB VRAM outperform Quadro RTX 4000's 7.1 TFLOPS and 8 GB for large-scale training.
What are the TDP ratings?▾
MI300X consumes 750W for high-density compute. Quadro RTX 4000 uses 160W, ideal for efficient workstations.
Which is cheaper to rent, the MI300X or the Quadro RTX 4000?▾
Cloud rental prices for both the MI300X and Quadro RTX 4000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.
How much VRAM does the MI300X have compared to the Quadro RTX 4000?▾
The MI300X has 192 GB of HBM3 memory. The Quadro RTX 4000 has 8 GB of GDDR6 memory.
Can I find MI300X and Quadro RTX 4000 GPUs available to rent right now?▾
Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.
What is the main difference between the MI300X and the Quadro RTX 4000?▾
The MI300X uses the CDNA 3 architecture (2023) while the Quadro RTX 4000 uses Turing (2018). The MI300X delivers 184.1x the FP16 throughput and 12.7x the memory bandwidth of the Quadro RTX 4000.



