MI300X vs MI355X

CDNA 3vsCDNA 4Updated 36 days ago

The MI355X emerges as the clear winner for most AI use cases due to 76% higher FP16, 14x FP32 performance, 50% more VRAM, and 51% greater bandwidth at identical 750W TDP. Deploy MI300X only if availability and pricing from $0.50 per hour are priorities, as MI355X redefines efficiency for training and inference.

MI300X from $1.99/hr

Specifications Compared

SpecMI300XMI355X
TDP750W750W
VRAM192 GB288 GB
Memory TypeHBM3HBM3e
ArchitectureCDNA 3CDNA 4
Form FactorsOAMOAM
InterconnectInfinity Fabric, PCIe 5.0Infinity Fabric
FP8 Performance2,614 TFLOPS4,600 TFLOPS
FP16 Performance1,307 TFLOPS2,300 TFLOPS
FP32 Performance163 TFLOPS2300 TFLOPS
FP64 Performance81.7 TFLOPS72 TFLOPS
INT8 Performance2,614 TOPS4,600 TOPS
Memory Bandwidth5,300 GB/s8,000 GB/s

Performance Analysis

The MI355X demonstrates superior raw compute with 2300 TFLOPS FP16 compared to 1307 TFLOPS on MI300X, a 76% uplift ideal for AI training dominated by half-precision operations. FP32 performance leaps from 163 TFLOPS to 2300 TFLOPS, enabling 14x faster scientific simulations or graphics workloads requiring single-precision math. FP8 throughput doubles to 4600 TFLOPS from 2614 TFLOPS, accelerating quantized inference for large language models. This FP16/FP32 balance on MI355X suits mixed-precision pipelines, whereas MI300X favors FP16-heavy inference. Memory differences prove critical: 288 GB HBM3e versus 192 GB HBM3 supports 50% larger batch sizes in training, reducing overhead in transformer models exceeding 100 billion parameters. The 8000 GB/s bandwidth on MI355X versus 5300 GB/s minimizes data starvation, sustaining peak FLOPS during memory-bound tasks like diffusion models. Same 750W TDP ensures comparable power efficiency per socket.

Live Cloud Pricing

Real-time prices from 25+ providers. Updated every 60 seconds.

MI300X

ProviderGPU ModelVRAMHost SpecsRegionPriceStatusAction
RunPod
RunPod
AMD Instinct MI300X
192GB VRAM
$1.99/GPU/hr
Hot Aisle
Hot Aisle
AMD Instinct MI300X
192GB VRAM
$1.99/GPU/hr
Available
Cirrascale
Cirrascale
8×AMD Instinct MI300X
192GB VRAM
$3.08/GPU/hr
$24.64/hr total (8×)
Crusoe
Crusoe
AMD Instinct MI300X
192GB VRAM
$3.45/GPU/hr
Cirrascale
Cirrascale
8×AMD Instinct MI300X
192GB VRAM
$3.47/GPU/hr
$27.76/hr total (8×)

Compare real-time pricing across 25+ providers

When to Choose the MI300X

Select the MI300X for immediate deployment in production environments. Nine live cloud offers start at $0.50 per hour with an average of $2.63 per hour, providing cost-effective access without waiting for MI355X availability. PCIe 5.0 support aids integration into existing data centers, and 192 GB HBM3 suffices for models up to 70 billion parameters in fine-tuning or inference at scale.

When to Choose the MI355X

Choose the MI355X for future-proofing demanding AI pipelines. Its 288 GB HBM3e and 8000 GB/s bandwidth handle massive datasets in LLM training, supporting batch sizes 50% larger than MI300X limits. Balanced 2300 TFLOPS across FP16 and FP32 excels in versatile workloads like scientific computing requiring high FP32 throughput.

Use Cases

LLM Training
MI355X

MI355X delivers 2300 TFLOPS FP16 and 288 GB VRAM, enabling 76% faster training and 50% larger batches than MI300X's 1307 TFLOPS FP16 and 192 GB.

LLM Inference
MI355X

FP8 at 4600 TFLOPS on MI355X doubles MI300X's 2614 TFLOPS for quantized serving, with 8000 GB/s bandwidth sustaining high throughput.

Fine-tuning
MI355X

288 GB HBM3e supports larger models during fine-tuning, and balanced FP32 at 2300 TFLOPS outperforms MI300X's 163 TFLOPS.

Stable Diffusion
Either

MI300X handles diffusion at 1307 TFLOPS FP16 with available pricing; MI355X accelerates via 2300 TFLOPS but awaits launch.

Scientific Computing
MI355X

MI355X's 2300 TFLOPS FP32 provides 14x speedup over MI300X's 163 TFLOPS for simulations, with Infinity Fabric optimizing multi-GPU scaling.

Frequently Asked Questions

Which architecture is newer?

MI355X uses CDNA 4 from 2025, advancing beyond MI300X's CDNA 3 of 2023. Interconnect includes Infinity Fabric on both. Compute balances shift to FP32 parity on MI355X.

Which is cheaper to rent, the MI300X or the MI355X?

Cloud rental prices for both the MI300X and MI355X vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the MI300X have compared to the MI355X?

The MI300X has 192 GB of HBM3 memory. The MI355X has 288 GB of HBM3e memory.

Can I find MI300X and MI355X GPUs available to rent right now?

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the MI300X and the MI355X?

The MI300X uses the CDNA 3 architecture (2023) while the MI355X uses CDNA 4 (2025). The MI355X delivers 1.8x the FP16 throughput and 1.5x the memory bandwidth of the MI300X.

MI300X vs MI355X: 288GB HBM3e vs 192GB HBM3 | GPUPerHour