B300 SXM6 vs Quadro RTX 4000

Blackwell UltravsTuringUpdated 35 days ago

The NVIDIA B300 SXM6 triumphs for prevalent AI and HPC use cases: 288 GB VRAM and 2250 TFLOPS FP16 enable large-scale training and inference unattainable on Quadro RTX 4000's 8 GB and 7.1 TFLOPS. Despite higher $6.44 per hour average cost, performance justifies it for modern demands.

B300 SXM6 from $7.39/hrQuadro RTX 4000 from $0.56/hr

Specifications Compared

SpecB300QUADRO-RTX-4000
TDP1200W160W
VRAM288 GB8 GB
Memory TypeHBM3eGDDR6
ArchitectureBlackwell UltraTuring
Form FactorsSXMPCIe
InterconnectNVSwitch, NVLink
FP8 Performance4,500 TFLOPS
FP16 Performance2,250 TFLOPS7.1 TFLOPS
FP32 Performance90 TFLOPS7.1 TFLOPS
FP64 Performance45 TFLOPS
INT8 Performance4,500 TOPS
Memory Bandwidth12,000 GB/s416 GB/s

Performance Analysis

The B300 vastly outperforms the Quadro RTX 4000 in compute: 2250 TFLOPS FP16 and 90 TFLOPS FP32 on B300 versus 7.1 TFLOPS for both on Quadro. This disparity accelerates deep learning training, where FP16 handles mixed-precision computations over 300 times faster on B300, reducing epoch times dramatically for models like transformers.

Memory capacity defines workload feasibility: B300's 288 GB HBM3e supports massive batch sizes in LLM training, fitting entire datasets that exceed Quadro's 8 GB GDDR6 limit. Bandwidth reinforces this: 12000 GB/s on B300 enables rapid data movement for inference at scale, while 416 GB/s on Quadro constrains throughput, leading to smaller batches and slower iterations.

Power draw reflects intent: B300's 1200W TDP suits datacenter cooling for sustained peaks, including 4500 TFLOPS FP8 for inference, whereas Quadro's 160W fits edge or workstation use without high infrastructure costs.

Live Cloud Pricing

Real-time prices from 25+ providers. Updated every 60 seconds.

B300 SXM6

ProviderGPU ModelVRAMHost SpecsRegionPriceStatusAction
RunPod
RunPod
NVIDIA B300 SXM6
262GB VRAM
$7.39/GPU/hr
VERDA
VERDA
NVIDIA B300 SXM6
262GB VRAM
$7.50/GPU/hr
Available
VERDA
VERDA
2×NVIDIA B300 SXM6
262GB VRAM
$7.50/GPU/hr
$15.00/hr total (2×)
Available
VERDA
VERDA
8×NVIDIA B300 SXM6
262GB VRAM
$7.50/GPU/hr
$60.00/hr total (8×)
Available
Scaleway
Scaleway
8×NVIDIA B300 SXM6
262GB VRAM
$8.73/GPU/hr
$69.84/hr total (8×)
Available

Quadro RTX 4000

ProviderGPU ModelVRAMHost SpecsRegionPriceStatusAction
Paperspace
Paperspace
NVIDIA Quadro RTX 4000
8GB VRAM
$0.56/GPU/hr
Available
Paperspace
Paperspace
NVIDIA Quadro RTX 4000
8GB VRAM
$0.56/GPU/hr
Available
Paperspace
Paperspace
2×NVIDIA Quadro RTX 4000
8GB VRAM
$0.56/GPU/hr
$1.12/hr total (2×)
Available
Paperspace
Paperspace
NVIDIA Quadro RTX 4000
8GB VRAM
$0.56/GPU/hr
Available
Paperspace
Paperspace
2×NVIDIA Quadro RTX 4000
8GB VRAM
$0.56/GPU/hr
$1.12/hr total (2×)
Available

Compare real-time pricing across 25+ providers

When to Choose the B300 SXM6

Choose the NVIDIA B300 SXM6 for AI workloads demanding extreme scale: its 288 GB VRAM handles LLMs over 100 billion parameters, and 2250 TFLOPS FP16 speeds training by factors exceeding 300x over Quadro RTX 4000. Datacenter setups leverage 12000 GB/s bandwidth and NVLink for distributed systems.

High-throughput inference benefits from 4500 TFLOPS FP8, ideal for real-time serving at $2.45 per hour starting price.

When to Choose the Quadro RTX 4000

Opt for NVIDIA Quadro RTX 4000 in budget-conscious workstation scenarios: 160W TDP integrates into PCIe systems without datacenter power, at $0.56 per hour. It suffices for CAD rendering or light ML inference where 8 GB VRAM and 7.1 TFLOPS FP32 meet needs.

Legacy software optimized for Turing architecture avoids migration costs, prioritizing affordability over scale.

Use Cases

LLM Training
B300 SXM6

B300's 288 GB VRAM fits massive models, and 2250 TFLOPS FP16 accelerates training over 300x faster than Quadro's 7.1 TFLOPS.

LLM Inference
B300 SXM6

4500 TFLOPS FP8 and 12000 GB/s bandwidth on B300 support high-throughput serving; Quadro's 8 GB VRAM limits model sizes.

Fine-tuning
B300 SXM6

90 TFLOPS FP32 and 288 GB capacity handle parameter-efficient tuning; Quadro lacks bandwidth at 416 GB/s for efficient batches.

Stable Diffusion
B300 SXM6

B300's FP16 performance generates images rapidly at scale; 8 GB on Quadro restricts resolution and batch sizes.

Scientific Computing
B300 SXM6

1200W TDP and NVLink scaling suit simulations needing 288 GB VRAM; Quadro's 160W fits only small datasets.

Frequently Asked Questions

What is the VRAM difference between NVIDIA B300 SXM6 and Quadro RTX 4000?

B300 SXM6 offers 288 GB HBM3e VRAM, enabling large model hosting. Quadro RTX 4000 provides 8 GB GDDR6, suitable for smaller workloads only.

How do cloud prices compare for these GPUs?

B300 SXM6 starts at $2.45 per hour, averaging $6.44 across 7 offers. Quadro RTX 4000 is $0.56 per hour average across 5 offers.

What architectures power these GPUs?

B300 uses Blackwell Ultra from 2025 with NVSwitch interconnect. Quadro RTX 4000 relies on Turing from 2018 with PCIe form factor.

Compare FP16 performance.

B300 delivers 2250 TFLOPS FP16 for AI acceleration. Quadro RTX 4000 achieves 7.1 TFLOPS, over 300 times slower.

What are the TDP ratings?

B300 requires 1200W for datacenter peaks. Quadro RTX 4000 uses 160W for workstation efficiency.

Which has higher memory bandwidth?

B300 provides 12000 GB/s for fast data transfer. Quadro RTX 4000 offers 416 GB/s, limiting batch processing.

Which is cheaper to rent, the B300 or the Quadro RTX 4000?

Cloud rental prices for both the B300 and Quadro RTX 4000 vary by provider, configuration, and availability. This page shows live pricing from 25+ providers updated every 60 seconds. Scroll to the Live Cloud Pricing section to compare current rates.

How much VRAM does the B300 have compared to the Quadro RTX 4000?

The B300 has 288 GB of HBM3e memory. The Quadro RTX 4000 has 8 GB of GDDR6 memory.

Can I find B300 and Quadro RTX 4000 GPUs available to rent right now?

Yes. This page shows real-time availability across 25+ cloud GPU providers. The Live Cloud Pricing section displays only in-stock offers with current pricing.

What is the main difference between the B300 and the Quadro RTX 4000?

The B300 uses the Blackwell Ultra architecture (2025) while the Quadro RTX 4000 uses Turing (2018). The B300 delivers 316.9x the FP16 throughput and 28.8x the memory bandwidth of the Quadro RTX 4000.

B300 SXM6 vs Quadro RTX 4000: 288GB vs 8GB | GPUPerHour